Synthesis, Characterization and Antitumor Activity of Polynuclear Solid Complex of Lanthanum with Dithiocarbaminoacetic Cobalt

Chinese Journal of Applied Chemistry ›› 1998, Vol. 0 ›› Issue (3): 39-42.

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Synthesis, Characterization and Antitumor Activity of Polynuclear Solid Complex of Lanthanum with Dithiocarbaminoacetic Cobalt

Wang Xuezhi¹, Zhang Jimin¹, Qin Honggui²

1. Department of Biochemical Engineering, Anhui Institute of Mechanical and Electrical Engineering, Wuhu 241000;
2. Department of Inspection, Yijishan Hospital of Wannan Medical College, Wuhu

Received:1997-11-24 Revised:1998-03-20 Published:1998-06-10 Online:1998-06-10

Abstract

Abstract: The new polynuclear solid complex of lanthanum(La) with dithiocarbaminoacetic cobalt [Co(HL)₂](L=^-S₂CNHCH₂CO₂^-) was synthesized in microwave oven at 60 ℃. The product was characterized by elemental analysis, IR spectrum, UV absorption spectrum,¹H NMR and molar conductance measurements. The results showed that the composition of the complex was La₂(CoL₂)₃. The preliminary bioassay showed that the complex could significantly inhibit the growth of liver cancer cell, but not affect on the growth of human liver cells.

Key words: lanthanum, dithiocarbaminoacetic cobalt, polynuclear complex, antitumor activity

Wang Xuezhi, Zhang Jimin, Qin Honggui. Synthesis, Characterization and Antitumor Activity of Polynuclear Solid Complex of Lanthanum with Dithiocarbaminoacetic Cobalt[J]. Chinese Journal of Applied Chemistry, 1998, 0(3): 39-42.

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Synthesis, Characterization and Antitumor Activity of Polynuclear Solid Complex of Lanthanum with Dithiocarbaminoacetic Cobalt

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