SYNTHESIS OF α-AMINO ACID VIA RAPID ALKYLATION UNDER MICROWAVE

Chinese Journal of Applied Chemistry ›› 1993, Vol. 0 ›› Issue (5): 108-109.

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SYNTHESIS OF α-AMINO ACID VIA RAPID ALKYLATION UNDER MICROWAVE

Deng Runhua, Mi Aiqiao, Jiang Yaozhong

Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, 610015 Chengdu

Received:1992-12-25 Revised:1993-05-21 Published:1993-10-10 Online:1993-10-10

Abstract

Abstract: Five α-amino acids were prepared by rapid alkylation without solvent under microwave and phase transfer catalysis. The alkylation lasted only for 1～2min. The α-amino acids were obtained by after hydrolysis. The overall yields were 43.6%～62.5%.

Key words: N-benzylidene glycinate, amino acid, synthesis microwave, phase transfer catalysis, alkylation, hydrolysis

Deng Runhua, Mi Aiqiao, Jiang Yaozhong. SYNTHESIS OF α-AMINO ACID VIA RAPID ALKYLATION UNDER MICROWAVE[J]. Chinese Journal of Applied Chemistry, 1993, 0(5): 108-109.

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SYNTHESIS OF α-AMINO ACID VIA RAPID ALKYLATION UNDER MICROWAVE

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