Ultrasonic Radiative Synthesis and Biological Activities of Morpholinomethylamino Containing 1,2,4-Triazole-5-thiones

doi:10.3724/SP.J.1095.2010.90820

Chinese Journal of Applied Chemistry ›› 2010, Vol. 27 ›› Issue (10): 1165-1171.DOI: 10.3724/SP.J.1095.2010.90820

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Ultrasonic Radiative Synthesis and Biological Activities of Morpholinomethylamino Containing 1,2,4-Triazole-5-thiones

ZHENG Yu-Guo, XUE Wei*, WEI Xue

(Key Laboratory of Green Pesticide and Bioengineering,Ministry of Education,Research and
Development Center for Fine Chemicals,Guizhou University,Guiyang 550025)

Received:2009-12-07 Revised:2010-02-20 Published:2010-10-10 Online:2010-10-10

Abstract

Abstract:

Eleven novel 1-(morpholinomethyl)-3-(3,4,5-trimethoxyphenyl)-4-substitute deneamino-1,2,4-triazole-5-thiones were designed and synthesized by mean of an ultrasonic radiation method and a ordinary heating process. Their structures were characterized by 1H NMR, 13C NMR, IR and elemental analyses. Preliminary bioassay showed that some of them exhibit certain inactivities to Cucumber mosaic virus(CMV).

Key words: ultrasonic irradiation, triazole, Imines, synthesis

CLC Number:

O632

ZHENG Yu-Guo, XUE Wei*, WEI Xue. Ultrasonic Radiative Synthesis and Biological Activities of Morpholinomethylamino Containing 1,2,4-Triazole-5-thiones[J]. Chinese Journal of Applied Chemistry, 2010, 27(10): 1165-1171.

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Ultrasonic Radiative Synthesis and Biological Activities of Morpholinomethylamino Containing 1,2,4-Triazole-5-thiones

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