Abstract:

A facile synthetic method for thienopyridine derivatives was developed via the reaction of 2-amino-thiophenes with acetoacetic ester and tin tetrachloride under heating. Four thienopyridine derivatives were obtained. The structures of the target compounds were determined by means of IR, 1H NMR, MS and elemental analysis. Preliminary biological activities of the four thienopyridine derivatives showed that most of them display high fungicidal activities and a certain extent of herbicidal activities as well.

Key words: Thieno[2,3-b]pyridine, acetoacetic ester, fungicidal activities, herbicidal activities