Chinese Journal of Applied Chemistry ›› 2017, Vol. 34 ›› Issue (12): 1413-1432.DOI: 10.11944/j.issn.1000-0518.2017.12.170309

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Recent Advances in Phosgene and Nerve Agents Responsive Fluorescent Probes

CHEN Jianhuaa,LI Dongyanga,LIU Shenghuaa,TAN Yingb*(),YIN Junab*()   

  1. aKey Laboratory of Pesticide and Chemical Biology,Ministry of Education,College of Chemistry,Central China Normal University,Wuhan 430079,China
    bThe State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology,Graduate School at Shenzhen,Tsinghua University,Shenzhen,Guangdong 518055,China
  • Received:2017-08-31 Accepted:2017-10-09 Published:2017-12-04 Online:2017-12-04
  • Contact: TAN Ying,YIN Jun
  • Supported by:
    Supported by the National Natural Science Fundation of China(No.21676113)

Abstract:

Highly toxic agents, such as phosgene and nerve agents, cause severe threats to public security and humankind. In contrast to traditional ways, the approaches to detect phosgene and nerve agents are expected to be effective detection in vivo. Fluorescent probes have been applied widely in various research fields due to their high selectivity and sensitivity, excellent cell permeability and so on. Herein, we review recent advances relating to fluorescent probes for phosgene and nerve agents and prospect their future developments.

Key words: fluorescent probes, phosgene, nerve agents