Synthesis and Biological Activity of Novel Triazoleamide-1,4-Pentadien-3-one Derivatives

doi:10.11944/j.issn.1000-0518.2015.04.140251

Chinese Journal of Applied Chemistry ›› 2015, Vol. 32 ›› Issue (4): 405-411.DOI: 10.11944/j.issn.1000-0518.2015.04.140251

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Synthesis and Biological Activity of Novel Triazoleamide-1,4-Pentadien-3-one Derivatives

ZHENG Yuguo^*, DENG Zhao, SONG Song, ZHOU Cai, LUO Mingzuo, NING Yan, GUO Qingqing

Institute of Green Chemistry-Synthesis Technology,Key Laboratory of Research and Development of Ethnomedicinal Biological Resources,Xingyi Normal University for Nationalities,Xingyi,Guizhou 562400,China

Received:2014-07-21 Revised:2015-01-27 Published:2015-04-10 Online:2015-04-10
Contact: Corresponding author:ZHENG Yuguo, associate professor; Tel/Fax:0859-3222483; E-mail:yuguobaolong@163.com; Research interests:design and development of novel pesticide
Supported by:
Supported by Science and Technology Foundation of Guizhou Province(No.[2012]2326), the Higher Educational Quality and Reform Project of Guizhou Province(No.[2012]426, No.[2013]446), Science and Technology Planning Project of Qianxinan Prefecture(No.2012-4, No.2013-7), the Natural Science Foundation of Xingyi Normal University for Nationnality(No.llxyy202)

Abstract

Abstract:

Using acetone and 2-hydroxybenzaldehyde as starting materials, nine novel curcumin derivatives containing 1,2,4-triazole and amide units were synthesized. The structures were confirmed by ¹H NMR, ¹⁹F NMR, IR and elemental analysis. The preliminary result of bioassay by airbrush spraying shows that some of the compounds obtianed exhibit weak to moderate insecticidal activity.

Key words: curcumin derivatives, triazole, synthesis, biological activity

CLC Number:

O626.2

ZHENG Yuguo , DENG Zhao, SONG Song, ZHOU Cai, LUO Mingzuo, NING Yan, GUO Qingqing. Synthesis and Biological Activity of Novel Triazoleamide-1,4-Pentadien-3-one Derivatives[J]. Chinese Journal of Applied Chemistry, 2015, 32(4): 405-411.

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Synthesis and Biological Activity of Novel Triazoleamide-1,4-Pentadien-3-one Derivatives

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