Solid Phase Grinding Synthesis and Plant Growth Activities of Arylureido-acylthiourea Derivatives

doi:10.3724/SP.J.1095.2013.20578

Chinese Journal of Applied Chemistry

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Solid Phase Grinding Synthesis and Plant Growth Activities of Arylureido-acylthiourea Derivatives

DUAN Zhifang, LI Chongbi^*, WU Xufang, CHEN Gang

(College of Life Science，Biopharmaceutical Research and Development Center,Zhaoqing University,Zhaoqing 526061,China)

Received:2012-12-11 Revised:2013-03-28 Published:2013-12-10 Online:2013-12-10

Abstract

Abstract: Eleven new arylureido-acylthiourea derivatives have been synthesized by solid phase grinding under solvent-free conditions at room temperature. Their structures were confirmed by 1H NMR, IR and elementary analysis. The results of biological activity tests show that some target compounds have evident activity on plant growth when the concentration is 10 mg/L. Among these, N-phenylureido-N′-cinnamic acylthiourea and N-p-methylphenylureido N′-cinnamic acylthiourea have good auxins activity, the effects are 54.13% and 46.79%, respectively, while N-p-methylphenylureido-N′-cinnamic acylthiourea and N-p-methylphenylureido-N′-phenoxyacetyl thiourea have excellent activity of cytokinin, the effects are 55.11% and 51.14%, respectively.

Key words: arylureido-acylthiourea, solid phase grinding synthesis, biological activity

CLC Number:

O621.3

DUAN Zhifang, LI Chongbi*, WU Xufang, CHEN Gang. Solid Phase Grinding Synthesis and Plant Growth Activities of Arylureido-acylthiourea Derivatives[J]. Chinese Journal of Applied Chemistry, DOI: 10.3724/SP.J.1095.2013.20578.

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Solid Phase Grinding Synthesis and Plant Growth Activities of Arylureido-acylthiourea Derivatives

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