Abstract:

Two novel(carbonyl) triruthenium metal clusters were separated with cellulose tris(3,5dimethylphenylcarbamate)(CDMPC) as chiral stationary phase. The effects of the optimal conditions were determined according to the effects of the mobile phase composition, the flow rate of the mobile phase and the solvents of the samples etc on the chiral separation of the metal clusters. The results show that good chiral separations of cluster 1 and cluster 2 were obtained respectively using the mobile phase with ethanol(V(hexane)∶V(ethanol)=95∶5) and 2-propanol(V(hexane)∶V(2-propanol)=90∶10). The solvents of the samples with similar composition to that of the mobile phase were beneficial to the chiral separation of the clusters. The structures of the metal-chelated ligand exerted an important influence on the retention and chiral separation of the metal clusters. The Rs of the clusters were above 1.5 under the optimal conditions.

Key words: Novel metal clusters, CDMPC, Chiral separation, HPLC