Chinese Journal of Applied Chemistry ›› 1993, Vol. 0 ›› Issue (1): 62-65.

• Full Papers • Previous Articles     Next Articles

STUDY ON PORPHYRIN COMPOUNDS ⅩⅩⅢ.SYNTHESIS AND PHOTOSENSITIVITY OF PORPHYRIN-CHOLESTEROL ESTER

Ke Hanzhong1, Xia Suzhen1, Zhou Xiang1, Huang Suqiu1, Li Lezhen2, Xu Jingya2, Yang Jun2   

  1. 1. Department of Chemistry, Wuhan University, 40072 Wuhan;
    2. Hubei Academy of Chinese Traditional Medicine and Phamacy, Wuhan
  • Received:1992-02-24 Revised:1992-06-24 Published:1993-02-10 Online:1993-02-10

Abstract: Six cholesterol-porphyrins have been synthesized. The photoradiative effect on cancer and the interaction of compounds 5 and 9 with red cells have been examined. The results shown that to some degree, they showed a destructive effect on Ehrlich ascitogenous cells and Mouse ascitic breast carcionma cells directly,but very little photo-hemolytic action.

Key words: porphyrin, synthesis, photo-hemolytic action