Synthesis and Biological Activities of Novel Bistriazolyl-3(2H)-pyridazinones

doi:10.3724/SP.J.1095.2011.00623

Chinese Journal of Applied Chemistry ›› 2011, Vol. 28 ›› Issue (09): 1028-1034.DOI: 10.3724/SP.J.1095.2011.00623

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Synthesis and Biological Activities of Novel Bistriazolyl-3(2H)-pyridazinones

ZHENG Yuguo^1,2, WEI Xue¹, GUO Qingqing¹, LU Ping¹, WANG Zhenchao¹, XUE Wei^1*

(1.Key Laboratory of Green Pesticide and Bioengineering, Ministry of Education,
Research and Development Center for Fine Chemicals,Guizhou University,Guiyang 550025;
2.Department of Chemistry and Biology,Xingyi Normal College,Xingyi)

Received:2010-10-19 Revised:2010-12-08 Published:2011-09-10 Online:2011-09-10

Abstract

Abstract:

Nine novel pyridazinone derivatives containing 1,2,4-triazolo and Schiff base were synthesized. Their structures were characterized by 1H NMR, 13C NMR, IR and elemental analyses. The preliminary bioassay showed that, under 500 mg/L concentrations, some of them exhibited certain anti-cucumber mosaic virus(CMV), G. zeae, F.oxysporum and C.mandshurica activities and fungicidal activities.

Key words: triazole, pyridazinones, imines, bioactivity, synthesis

CLC Number:

O632

ZHENG Yuguo1,2, WEI Xue1, GUO Qingqing1, LU Ping1, WANG Zhenchao1, XUE Wei1*. Synthesis and Biological Activities of Novel Bistriazolyl-3(2H)-pyridazinones[J]. Chinese Journal of Applied Chemistry, 2011, 28(09): 1028-1034.

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Synthesis and Biological Activities of Novel Bistriazolyl-3(2H)-pyridazinones

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