Chinese Journal of Applied Chemistry ›› 2018, Vol. 35 ›› Issue (9): 984-992.DOI: 10.11944/j.issn.1000-0518.2018.09.180172

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Surface-Enhanced Raman Spectroscopy: Applications and Perspectives

ZHU Yuezhou,ZHANG Yuejiao,LI Jianfeng(),REN Bin,TIAN Zhongqun()   

  1. College of Chemistry and Chemical Engineering,Xiamen University,Fujian,Xiamen 361005,China
  • Received:2018-05-14 Accepted:2018-05-22 Published:2018-09-01 Online:2018-08-06
  • Contact: LI Jianfeng,TIAN Zhongqun
  • Supported by:
    Supported by the National Natural Science Foundation of China(No.21533006, No.21522508, No.21775127)


Surface-enhanced Raman spectroscopy(SERS) is a fingerprint spectroscopic technique with ultra-high sensitivity. It has been widely used in surface science, material science, biomedicine, drug analysis, food safety inspection, and pollutant detection, as a promising technique for trace analysis. In this paper, we comprehensively reviewed the development and applications of SERS and related techniques, including tip-enhanced Raman spectroscopy(TERS), shell-isolated nanoparticle-enhanced Raman spectroscopy(SHINERS), and discussed its research frontiers and development directions in the future.

Key words: surface-enhanced Raman spectroscopy, tip-enhanced Raman spectroscopy, shell-isolated nanoparticle-enhanced Raman spectroscopy, surface plasmon resonance