Progress in Biological Nanopore-based Analysis Technology

doi:10.11944/j.issn.1000-0518.2017.08.170103

Chinese Journal of Applied Chemistry ›› 2017, Vol. 34 ›› Issue (8): 855-867.DOI: 10.11944/j.issn.1000-0518.2017.08.170103

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Progress in Biological Nanopore-based Analysis Technology

SHANG Jizhen^a^b,LI Zhi^b,XI Dongmei^b^*(),ZHANG Shusheng^b^*()

^aThe Key Laboratory of Life-Organic Analysis,College of Chemistry and Chemical Engineering,Qufu Normal University,Qufu,Shandong 273165,China
^bShandong Provincial Key Laboratory of Detection Technology for Tumor Makers,College of Chemistry and Chemical Engineering,Linyi University,Linyi,Shangdong 276005,China

Received:2017-04-05 Accepted:2017-05-22 Published:2017-07-25 Online:2017-07-25
Contact: XI Dongmei,ZHANG Shusheng
Supported by:
Supported by the National Natural Science Foundation of China(No.21405073, No.21535002)

Abstract

Abstract:

Biological nanopore sensing has been developed as an attractive single-molecule tool with advantages of being rapid, low-cost, and label-free. Nanopores are not only being widely developed for DNA sequencing, but they also have been utilized to analyze a wide range of analytes at the single-molecule level. This review summarizes and prospects the principle of the nanopore analysis and nanpore category, with an emphasis on the progress in nanopore-based DNA sequencing and single-molecule analysis.

Key words: biological nanopore, DNA sequencing, single-molecule analysis

SHANG Jizhen,LI Zhi,XI Dongmei,ZHANG Shusheng. Progress in Biological Nanopore-based Analysis Technology[J]. Chinese Journal of Applied Chemistry, 2017, 34(8): 855-867.

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Progress in Biological Nanopore-based Analysis Technology

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