应用化学 ›› 2010, Vol. 27 ›› Issue (12): 1381-1385.DOI: 10.3724/SP.J.1095.2010.00190

• 研究论文 • 上一篇    下一篇

甲胺基阿维菌素苯甲酸盐微胶囊的制备与表征

李伟,路福绥*,郭雯婷,李慧   

  1. (山东农业大学化学与材料科学学院 泰安 271018)
  • 收稿日期:2010-03-18 修回日期:2010-05-24 出版日期:2010-12-10 发布日期:2010-12-10
  • 通讯作者: 路福绥,男,教授,博士生导师; E-mail:lfs@sdau.edu.cn; 研究方向:水基化农药剂型加工技术及原理
  • 基金资助:
    山东省自然科学基金资助项目(ZR2009DM032)

Preparation and Characterization of Emamectin Benzoate Microcapsules

LI Wei, LU Fu-Sui*, GUO Wen-Ting, LI Hui   

  1. (College of Chemistry and Materials Science,Shandong Agricultural University,Taian 271018)
  • Received:2010-03-18 Revised:2010-05-24 Published:2010-12-10 Online:2010-12-10

摘要:

以三聚氰胺-甲醛树脂为壁材,采用原位聚合法制备了甲胺基阿维菌素苯甲酸盐微胶囊,研究了三聚氰胺与甲醛的质量比、芯壁比、乳化剂、搅拌速度与时间、pH值、温度等因素对微胶囊形成的影响,对制备的微胶囊进行了表征,测定了甲维盐微胶囊化前后的光解率。 结果表明,三聚氰胺与甲醛质量比为1∶2、芯材与壁材质量比为3∶2、以质量分数1%羟乙基纤维素(HEC)为乳化剂、在1000 r/min搅拌速度下、pH=5.0和50 ℃保温2 h可制备出形貌较好、平均粒径4.4 μm的甲维盐微胶囊。 红外光谱分析证明,甲维盐已完全被包覆在微胶囊中。 紫外分光光度法测定其缓释性能良好。 光解实验表明,微胶囊化可有效降低甲维盐原药的光解。

关键词: 甲胺基阿维菌素苯甲酸盐, 微胶囊, 原位聚合法, 制备条件, 表征

Abstract:

Using formaldehyde and melamine as wall materials, encapsulated emamectin benzoate-toluene microcapsules were prepared via an in-situ polymerization process. The experimental results show that well defined microcapsules with uniform particle size around 4.4 μm could be formed when the mass ratio of melamine to formaldehyde is 1∶2, core to wall is 3 to 2, using 1% mass fraction of HEC as emulsifying agent, the stirring ratio is 1000 r/min, pH value is 5.0, the temperature and heating time are 50 ℃ and 2 h, respectively. An improved photodegradation of emamectin benzoate microcapsules toward UV light could be achieved. Fourier-transform infrared spectroscopy(FT-IR) results also demonstrate the successful encapsulation of emamectin benzoate within the wall material.

Key words: emamectin benzoate, microcapsules, in-situ polymerization, preparation conditions, characterization

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