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邻苯二甲酸二异辛酯表面印迹聚合物的制备及其固相萃取应用

刘玉楠1,张朝晖1,2*,张明磊1,陈星1,陈红军1,聂利华2   

  1. (1.吉首大学化学化工学院 吉首 416000；2.湖南大学化学生物传感与计量国家重点实验室 长沙 410082)
  • 收稿日期:2012-05-18 修回日期:2012-07-23 出版日期:2013-03-10 发布日期:2013-03-10
  • 通讯作者: 张朝晖，副教授; Tel/Fax:0743-8563911; E-mail:zhaohuizhang77@163.com; 研究方向：印迹色谱分析和电化学分析
  • 基金资助:
    国家自然科学基金(21005030)湖南省教育厅重点项目(10A099)资助

Preparation and Solid-phase Extraction Applied of Di(2-ethylhexyl)phthalate Surface Imprinted Polymers

LIU Yunan1, ZHANG Zhaohui1,2*, ZHANG Minglei1, CHEN Xing1, CHEN Hongjun1, NIE Lihua2   

  1. (1.College of Chemistry and Chemical Engineering,Jishou University,Jishou 416000,China；
    2.State Key Laboratory of Chemo/Biosensing and Chemometrics,Hunan University,Changsha 410082,China)
  • Received:2012-05-18 Revised:2012-07-23 Published:2013-03-10 Online:2013-03-10

PDF

1667

被引次数

17 | 7

摘要： 采用复合二氧化硅微球(H-SiO2)作为载体，以邻苯二甲酸二异辛酯(DIOP)为模板分子，甲基丙烯酸(MAA)为功能单体，乙二醇二甲基丙烯酸酯(EGDMA)为交联剂，制备了邻苯二甲酸二异辛酯表面印迹聚合物(H-SiO2@MIP)。 分别采用扫描电子显微镜和红外光谱对该印迹聚合物进行了观察和表征，结果表明，制备出的印迹聚合物呈球形，印迹壳层厚度为60~70 nm。 采用高效液相色谱技术对该印迹聚合物的吸附性能进行了检测，结果表明，该印迹聚合物对塑化剂DIOP表现出特异性吸附性能，最大吸附容量为50.35 mg/g，DIOP对于邻苯二甲酸二丁酯(DBP)和邻苯二甲酸二乙酯(DEP)的选择因子(β)分别为2.31和2.47。 将该印迹聚合物装填于固相萃取柱中，结合液相色谱检测技术，能对牛奶样品中的塑化剂DIOP进行有效分离、富集和检测。

关键词: 印迹聚合物, 邻苯二甲酸二异辛酯, 表面印迹, 固相萃取

Abstract: Surface molecularly imprinted polymer(H-SiO2@MIP) based on hybrid silica microspheres was prepared by using di(2-ethylhexyl)phthalate(DIOP) as the template molecule, methacrylic acid(MAA) as the functional monomer and ethylene glycol dimethacrylate(EGDMA) as the cross-linking agent. The H-SiO2@MIP was characterized by scanning electron microscope(SEM) and infrared spectroscopy(IR). The results showed that DIOP imprinted layer was grafted on particles surface successfully. The H-SiO2@MIP has uniform spherical structure and the thickness of imprinted shell is about 60~70 nm. The adsorption properties were investigated by high performance liquid chromatography, and results demonstrated that the H-SiO2@MIP exhibited specific selectivity towards DIOP. The maximum adsorption capacity of H-SiO2@MIP was 50.35 mg/g, and the selectivity factor of DIOP towards dibutyl phthalate(DBP) and dimethyl phthalate(DEP) was 2.31 and 2.47, respectively. Packed into a solid-phase extraction(SPE) column, the H-SiO2@MIP could separate and enrich DIOP from milk sample.

Key words: imprinted polymer, di(ethylhexyl)phthalate, surface imprinting, solid-phase extraction

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