蒙药荜茇不同提取物的红外光谱

doi:10.19894/j.issn.1000-0518.200341

摘要/Abstract

摘要： 采用傅里叶变换红外光谱法(FT-IR)并借助于二阶导数谱研究了蒙药荜茇原药材及不同溶剂提取物(采用石油醚,95%乙醇和水)所含化学成分的红外谱图整体变化规律。结果表明:荜茇石油醚提取物的红外光谱图可见羰基的吸收峰(1722 cm^-1)和亚甲基的吸收峰(2927和2855 cm^-1)比较强,说明其中所含大量的小分子萜类、脂肪酸(酯)等低极性成分;95%乙醇提取物中可能含有芳酮类化合物及糖苷类化合物。水提取物中主要含鞣质及多糖类成分。 FT-IR能够简便、快速地提供蒙药不同提取物中主要化学成分的信息,可对其主体成分进行初步的识别,为制定下一步的提取方案和检测方法提供了方向性参考。

关键词: 荜茇, 傅里叶变换红外光谱, 提取物, 二阶导数红外光谱

Abstract: Fourier transform infrared (FT-IR) spectroscopy and its second derivative infrared spectroscopy were used to analyze the chemical compositions of different solvents extracts (petroleum ether, 95% ethanol and water) of Mongolian medicine fructus piperis longi . The results show that the absorption peaks of carbonyl (1722 cm^-1) and methylene (2927 and 2855 cm^-1) are stronger, which meant it has a number of low polarity components, including small molecules terpenoids, fatty acids or ester, and etc. The 95% ethanol extracts may contain aromatic ketones and glycoside compounds. The water extract mainly contains tannins and polysaccharides. The FT-IR spectra can provide the information of the main chemical components in different Mongolian medicine extracts easily and quickly, meanwhile its main components can be identified preliminarily by the FT-IR. Moreover, it can provide a reference for the next extraction approach and detection method.

Key words: Fructus piperis longi, Fourier transform infrared spectroscopy, Extract, Second derivative spectra

中图分类号:

O657.3

张春晖, 刘西京, 章蓉, 图雅. 蒙药荜茇不同提取物的红外光谱[J]. 应用化学, 2021, 38(3): 271-275.

ZHANG Chun-Hui, LIU Xi-Jing, ZHANG Rong , TU Ya. Infrared Spectrum about the Different Extracts of Fructus Piperis Longi [J]. Chinese Journal of Applied Chemistry, 2021, 38(3): 271-275.

参考文献

[1] 奥·乌力吉, 布和巴特尔. 传统蒙药与方剂[M]. 呼和浩特:内蒙古科学技术出版社, 2013: 8.
AO W, BUHE B. Traditional Mongolian medicine and prescriptions[M]. Huhhot: Inner Mongolia Science and Technology Press, 2013: 8.
[2] 美丽, 张小飞, 陈红梅, 等. 荜茇在中医、蒙医中的应用概况及研究进展[J]. 中草药, 2018, 49(8): 1957-1963.
MEI L, ZHANG X F, CHEN H M, et al. Research progress and application of Piper longum in traditional Chinese medicine and traditional Mongolian medicine[J]. Chinese Tradit Herb Drugs, 2018, 49(8): 1957-1963.
[3] 包·照日格图, 李翀, 海银梅. 中医和蒙医临床应用荜茇异同浅析[J]. 上海中医药杂志, 2006, 40(2) :59-61.
BAO Z, LI C, HAI Y M.Compar ative study on the clinical uses of Piper Longum L. in traditional Chinese medicine and traditional Mongolian ethical medicine[J]. Shanghai J Tradit Chinese Med, 2006, 40(2): 59-61.
[4] 包雪梅, 那生桑, 陆景坤. 荜茇有效部位群的调血脂研究[J]. 中国中药杂志, 2013, 38(6): 909-913.
BAO X M, NA S S, LU J K.Studies of effective part group of piperine to regulating lipid[J]. China J Chinese Mater Med, 2013, 38(6): 909-913.
[5] 朱冬宁, 陈驰, 王淑美, 等. 网络药理学在中医药研究领域的应用进展[J]. 广东化工. 2018, 45(7): 157-158.
ZHU D N,CHEN C, WANG S M, et al. Application progress of network pharmacology in the research of traditional Chinese medicine[J], Guangdong Chem Ind, 2018, 45(7): 157-158.
[6] 李丹, 杨异卉, 赖睿智, 等. 荜茇化学成分和药理活性研究现状[J]. 中国临床药理学杂志, 2017, 33(6): 565-566.
LI D, YANG Y H, LAI R Z, et al. Status of chemical constituents and pharmacological activities of Piper Longum L.[J] . Chinese J Clin Pharm, 2017, 33(6): 565-569.
[7] 董岩, 魏兴国, 崔庆新, 等. 荜拨挥发油化学成分分析[J]. 山东中医杂志 , 2004, 23(1): 43-45.
DONG Y, WEI G X, CUI Q X, et al. Analysis on chemical constituents of essential oil from Piper Longum L.[J], Shandong J Tradit Chinese Med, 2004, 23(1): 43-45.
[8] 敖道夫, 额尼日勒, 王布和朝鲁, 等. 荜茇挥发油及其含药血清GC-MS特征图谱分析[J]. 中华中医杂志, 2019(9): 4360-4363.
AO D F, ENIRILE, WANG B, et al. Analysis of characteristic chromatograms of essential oil of Biba in serum[J]. China Tradit Chinese Med Pharm, 2019(9): 4360-4363.
[9] 孙素琴, 周群, 刘军, 等. 真伪半夏二维相关红外光谱法的鉴别研究[J]. 光谱学与光谱分析, 2004, 24(4): 427-430.
SUN S Q, ZHOU Q, LIU J, et al. Study on the identification of standard and false BanXia by two-dimensional infrared correlation spectroscopy[J]. Spectrosc Spectr Anal, 2004, 24(4): 427-430.
[10] LIN Z, SUN S Q, ZHOU Q, et al. 2D-IR correlation analysis of deteriorative process of traditional Chinese medicines “Qing Kai Ling” injection[J]. J Pharm Biomed Anal, 2003, 30:1491-1498.