Construction of Molecular Beacons and Their Research Progress of Application

doi:10.3724/SP.J.1095.2013.30116

Chinese Journal of Applied Chemistry

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Construction of Molecular Beacons and Their Research Progress of Application

XIANG Dongshan^1,2*, ZHAI Kun²

(1.Key Laboratory of Biologic Resources Protection and Utilization of Hubei Province;
2.School of Chemical and Environmental Engineering,Hubei University for Nationalities,Enshi 445000,China)

Received:2013-03-08 Revised:2013-05-25 Published:2014-01-10 Online:2014-01-10

Abstract

Abstract: Molecular beacon is an oligonucleotide probe of fluorescence. Molecular beacons are playing a very important role in molecular biology, genetics and molecular medicine because they have been shown to have very high selectivity, high sensitivity, and real-time detection capabilities. The structures and working mechanisms of a variety of novel molecular beacons have been outlined here. We briefly summarize the application of molecular beacon technology in the field of life sciences, and propose the prospect this technology.

Key words: molecular beacons, construction, biochemical analysis, application

CLC Number:

O651

XIANG Dongshan1,2*, ZHAI Kun2. Construction of Molecular Beacons and Their Research Progress of Application[J]. Chinese Journal of Applied Chemistry, DOI: 10.3724/SP.J.1095.2013.30116.

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Construction of Molecular Beacons and Their Research Progress of Application

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