Abstract: The biological effects of Ge compounds on the rat with diabete mellitus is reported.The effects of Ge-132 on the pancreatic cells of young rat in vitro have beenexamined in order to elucidate the cytology mechanism.The results show that both 0.01mmol/L and 1 mmol/L Ge-132 did not affect the morphology of the pancreatic cell.However, Ge-132 in concentration of 0.01 mmol/L revealed an obvious promotion of the pancreasof young rats to secrete insulin.The effect of Ge-132 was compared with that of GeO₂.

Key words: Ge-132, pancreatic cell, insulin, pharmaceutical activity