Chinese Journal of Applied Chemistry ›› 2010, Vol. 27 ›› Issue (02): 125-131.DOI: 10.3724/SP.J.1095.2010.90384

• Original Articles •     Next Articles

Recent Progress in DNA origami

FU Yan-Ming1,3, ZHANG Zhao2, LI Can2, SHI Yong-Yong2, YAN Xiu-Feng1, FAN Chun-Hai3*   

  1. (1.Northeast Forestry University,Harbin;
    2.Bio-X Center,Shanghai Jiao Tong University,Shanghai;
    3.Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800)
  • Received:2009-06-08 Revised:2009-07-31 Online:2010-02-10 Published:2010-02-10


DNA origami is a new DNA self-assembly method raised recently, and it is a major innovation in the field of DNA nanotechnology and self-assembly. Compared to the traditional DNA self-assembly, DNA origami uses a long single-stranded genomic DNA with a series of short complementary single-strands DNA, and it can construct more complex and more controllable nanopatterns or structures, with a wide range of potential applications in the emerging field of nanotechnology. In this paper, we briefly introduced the principles of DNA origami, then reviewed the origin and development of DNA origami and its potential applications in the field of DNA chip, nanocomponents and nanomaterials. At the end we discussed the future directions of development.

Key words: DNA self-assembly,DNA origami,Nanotechnology

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