Chinese Journal of Applied Chemistry

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Application of Microreactor Technology in Synthetic Chemistry

HE Wei1, FANG Zheng1, CHEN Ketao2, WANG Zhidong1, GUO Kai3*   

  1. (1.School of Pharmaceutical;2.College of Sciences;3.College of Biotechnology and
    Pharmaceutical Engineering,Nanjing University of Technology,Nanjing 210009,China)
  • Received:2012-12-31 Revised:2013-05-03 Published:2013-12-10 Online:2013-12-10

Abstract: Micro Reactor Technique(MRT), which shows great advantages in heat transfer, mass transfer and mixing, can enhance the mixing process and control the reaction temperature precisely. In addition, it can dramatically shorten the screening period and scale-up process. This review emphasized the application of the microreactor technology in liquid phase reaction, gas phase reaction and gas-liquid phase reaction in detail. Meanwhile, photochemistry and electrochemistry were introduced briefly. We also presented the existing problems in such technique.

Key words: microreactor, heat transfer, mass transfer, liquid phase microreaction, gas phase microreaction, gas-liquid phase microreaction

CLC Number: