Chinese Journal of Applied Chemistry ›› 1997, Vol. 0 ›› Issue (1): 77-79.

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Synthesis of α-Methylene-γ-Butyrolactones

Chen Zuxing, Li Yan, Huang Jingmei, Huang Jinxia, Xu Zhanghuang   

  1. Department of Chemistry, Hubei University, Wuhan 430062
  • Received:1996-03-11 Revised:1996-07-02 Published:1997-02-10 Online:1997-02-10

Abstract: The enolate, obtained by treatment of methyl 3-(diethylamino)propionate with lithium diisopropylamide, reacts with epoxides to give products which may be considered to be protected acrylate esters. α-Methylene-γ-butyrolactones were synthesized by lactonization after the one-pot deamination procedure.

Key words: methylene butyrolactone, methyl(diethylamino)propionate, expoxide