Chinese Journal of Applied Chemistry ›› 1996, Vol. 0 ›› Issue (3): 41-45.
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Dai Lerong, Yang Qingping, Wu Peiqiang
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Abstract: Phase behaviour and solubilization of cholesterol in liquid crystal phase of C12 (EO)4-H2O system and C12(EO)4-lecithin-H2O system were investigated.The phase diagram of C12(EO)4-lecithin-water-cholesterol system was similar to lecithin-water-cholesterol system.In C12(EO)4-H2O ststem,where cholesterol was solubilized,the concentration range of C12(EO)4 in liquid crystal was broader than that without cholesterol.The results of X-ray diffraction showed that,when cholesterol was solubilized into C12(EO)4-H2O lamellar liquid crystal,the thickness of amphiphile bilayer d0 increased,the amphiphile molecular array was more compact and the penetration of water molecules decreased.
Key words: polyoxyethylene ether, lyotropie liquid erystal, eholesterol, solubilization
Dai Lerong, Yang Qingping, Wu Peiqiang. Solubilization of Cholesterol in Polyoxyethylene Ether Lyotropic Liquid Crystal[J]. Chinese Journal of Applied Chemistry, 1996, 0(3): 41-45.
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