Abstract: Biological potential of tooth surface and dental pulp has been measured and stud-ied by electrochemical method.For the first time potential difference between these twoparts of tooth has been obtained experimentally,the statistical average being 11.1mV,Anexperimental method of simulating biological potential of living tooth has been establishedfor leaving body tooth.Ion transferred to tooth hard organism was studied by simulating thebiological potential of tooth.Change of biological potential of tooth in the real environmentof oral cavity has been discussed.Also the feasibility of two commonly used compounds of SrCl₂ and NaF for dental disease was discussed from the viewpoint of the effect of bioelectricfield.Scientific basis for the oral local administration has been provided.

Key words: bioelectrochemistry, biological potential, tooth, SrCl₂, NaF