Abstract: By reacting 2, 4-di-isocyanatotoluene with cholesterol and 1, 2-hydroxypropyl methacry-late, a new monomer containing cholesteric group was prepared. The monomer was then copolymerized with 1,2-hydroxypropyl methacrylate in different proportions. Copolymers with cholesteric ester side chain from 1,2-hydroxypropyl 2,4-diisocyanatotoluene methacrylate were prepared.The formation of monomer and copolymer has been identified by IR and NMR spectroscopic methods.