Abstract: Using o-dihydroxybenzene and 1,11-dichloro-3,6,9-trioxaundecane as raw materials, sodium hydroxide as template, DMF as solvent and appropriate amount of 2,6-di-tert-butyl-4-methylphenol as antioxidant, benzo-15-crown-5 was successfully synthesized under ultrasonication at temperature 60~70 ℃. Compared with traditional synthetic routes, reaction time could be reduced to within 2 h, and the yield reached up to 30.7%.

Key words: o-Dihydroxybenzene, dichloro-trioxaundecane, ultrasonic synthesis, benzo-15-crown-5