Hydroxyl Radical Scavenging Activity and Kinetics of Vitamin C

doi:10.11944/j.issn.1000-0518.2015.08.140427

Chinese Journal of Applied Chemistry ›› 2015, Vol. 32 ›› Issue (8): 948-954.DOI: 10.11944/j.issn.1000-0518.2015.08.140427

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Hydroxyl Radical Scavenging Activity and Kinetics of Vitamin C

LI Yan,GONG Shilei,CHE Ying,JIN Li'e,Yan Guolan()

College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan 030024, China

Published:2015-08-08 Online:2015-08-08
Contact: Yan Guolan
Supported by:

Abstract

Abstract:

For humanbeings, radicals scavenging plays an important role for maintaining the fundamental physiological and anti-ageing need. Comparison for competing scavenging ability of Vitamin C(V_C) with salicylic acid gives optimal scavenging condition for V_C. By fitting the Alberty equation, the maximum 46.23% clearance of ·OH by V_C reached when V_C concentration is 4.54 mmol/L at 47 ℃ for 90 min, and the maximum reaction rate is 0.11 mmol/(L·min). The dissociation constant for salicylic acid and V_C is 30.2 mmol/L and 1.2×10^-3 mmol/L, respectively. The experimental data are well-fitted with relative error of 1.66%~5.40%. This is helpful for the effective and scientific usage of V_C.

Key words: hydroxyl radical, ascorbic acid, clearance rate, reaction kinetics

CLC Number:

LI Yan, GONG Shilei, CHE Ying, JIN Li'e, Yan Guolan. Hydroxyl Radical Scavenging Activity and Kinetics of Vitamin C[J]. Chinese Journal of Applied Chemistry, 2015, 32(8): 948-954.

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Hydroxyl Radical Scavenging Activity and Kinetics of Vitamin C

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