聚苯乙烯负载氯化铁催化一锅法合成β-氨基酮类衍生物

doi:10.3724/SP.J.1095.2014.30401

摘要/Abstract

摘要： 制备了聚苯乙烯负载型氯化铁催化剂(PS-FeCl3)，并通过红外光谱、X射线衍射、扫描电子显微镜等技术手段进行了表征。在PS-FeCl3催化下，以苯乙酮、芳醛和芳胺为原料，采用一锅法Mannich反应合成了一系列β-氨基酮衍生物。制备的催化剂性能稳定，使用4次仍保持较高活性。

关键词: 聚苯乙烯负载氯化铁, &, beta, -氨基酮, Mannich反应, 一锅法

Abstract: A novel polystyrene-supported ferric chloride catalyst was prepared and characterized by IR, XRD and SEM. The catalyst exhibited excellent catalytic activities for the synthesis of β-amino ketone derivatives via one-pot Mannich reaction from acetophenone, aromatic aldehydes and aromatic amines. The catalyst could be recycled easily and the activity of the catalyst maintained after 4 cycles.

Key words: polystyrene-supported ferric chloride, &, beta, -amino ketone, Mannich reaction, one-pot method

中图分类号:

O621.3

肖立伟, 孔洁, 周秋香, 胡悦立. 聚苯乙烯负载氯化铁催化一锅法合成β-氨基酮类衍生物[J]. 应用化学, DOI: 10.3724/SP.J.1095.2014.30401.

XIAO Liwei*, KONG jie, ZHOU Qiuxiang, HU Yueli. One Pot Synthesis of β-Amino Ketone Derivatives Catalyzed by Polystyrene-supported Ferric Chloride[J]. Chinese Journal of Applied Chemistry, DOI: 10.3724/SP.J.1095.2014.30401.

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