应用化学 ›› 1998, Vol. 0 ›› Issue (3): 19-21.

• 研究论文 • 上一篇    下一篇

硫(硒)代磷酸酯-膦酸酯类化合物除草活性的构效关系

周嘉, 陈茹玉, 杨华铮, 杨秀凤, 杨光富   

  1. 南开大学元素有机化学研究所, 元素有机化学国家重点实验室 天津300071
  • 收稿日期:1997-09-23 修回日期:1997-12-23 出版日期:1998-06-10 发布日期:1998-06-10
  • 基金资助:
    国家自然科学基金

Studies on the Quantitative Structure-Activity Relationship(QSAR) of Thio(Seleno) Phosphate-phosphonate Herbicides

Zhou Jia, Chen Ruyu, Yang Huazheng, Yang Xiufeng, Yang Guangfu   

  1. Institute of Elemento-Organic Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071
  • Received:1997-09-23 Revised:1997-12-23 Published:1998-06-10 Online:1998-06-10

摘要: 利用与自由能有关的取代基物理化学参数,考察了硫(硒)代磷酸酯-膦酸酯类化合物对除草活性的相关性。根据Hansch方程及多元回归分析,进行了结构与活性定量关系的研究,建立了较好的结构与活性相关式。

关键词: 硫(硒)代磷酸酯-膦酸酯, 除草活性, 构效关系, 回归分析

Abstract: The quantitative relationship between the structure of thio(seleno) phosphate phosphonates and their herbicidal activity on the rape was investigated using physico chemical parameters of the substituents and regression analysis. Good QSAR results were obtained, which might be used in guiding the synthesis of compounds with higher activity.

Key words: thio(seleno) phosphate phosphonate, herbicidal activity, QSAR, regression ana-lysis