中华医学超声杂志

应用化学 ›› 1996, Vol. 0 ›› Issue (5): 97-99.

• 研究简报 • 上一篇    下一篇

对酞内酰胺苯磺酰氯与胺类化合物的衍生反应

崔同1, 傅承光2   

  1. 1. 河北农业大学食品科学系 保定 071001;
    2. 河北大学理化分析研究中心 保定
  • 收稿日期:1995-12-25 修回日期:1996-05-16 出版日期:1996-10-10 发布日期:1996-10-10

Derivatization of Amines with Phthalimidyl Benzene Sulphonyl Chloride

Cui Tong1, Fu Chengguang2   

  1. 1. Department of Food Science, Hebei Agriculture University, Baoding 071000;
    2. Research Centre of Physical and Chemical Analysis, Hebei University, Baoding
  • Received:1995-12-25 Revised:1996-05-16 Published:1996-10-10 Online:1996-10-10

PDF

326

被引次数

1

摘要： 对酞内酞胺苯磺酞抓(简称Phisyl-Cl)是一种新型高灵敏度荧光(紫外)衍生试剂,已作为高效液相色谱法柱前衍生试剂用于氨基酸、多胺及相关化合物、以及仲丁胺残留量的分析,目前尚未见有关该试剂应用方面的其他报道.为便于该试剂的推广应用,本文探讨其与胺类衍生反应的一些性质.

关键词: 对酞内酰胺苯磺酰氯, 胺类化合物, 衍生试剂, 衍生反应

Abstract: The kinetic study showed that the water content has an important effect on the hydrolysis rate of phthalimidyl benzene sulphonyl chloride(Phisyl-Cl). The PH of the reaction medium should be higher than 8.0 and 9.0 for derivatization with primary and secondary amines respectively. The hydrolysis of Phisyl-Cl is inhibited by adding solid NaHCO3 instead of its saturated solution to the medium to promote derivatization.

Key words: phthalimidylbenzene sulphonyl chloride, amine, derivatizing reagent, derivatization

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