应用化学 ›› 1996, Vol. 0 ›› Issue (2): 104-106.

• 研究简报 • 上一篇    下一篇

钼系杂多、同多配合物抗肿瘤活性(Ⅱ)

刘术侠, 刘彦勇, 刘杰, 李白涛, 王恩波   

  1. 东北师范大学化学系 长春 130024
  • 收稿日期:1995-08-25 修回日期:1995-12-14 出版日期:1996-04-10 发布日期:1996-04-10
  • 基金资助:
    国家自然科学基金;中国科学院长春应用化学研究所稀土化学与物理开放实验室资助

Antitumor Activity of Molybdenum Heteropoly Compounds

Liu Shuxia, Liu Yanyong, Liu Jie, Li Baitao, Wang Enbo   

  1. Department of Chemistry Northeast Normal University, Changchun 130024
  • Received:1995-08-25 Revised:1995-12-14 Published:1996-04-10 Online:1996-04-10

摘要: 多阴离子是一类多核配合物,可望成为新型的抗肿瘤药物.迄今发现,钥系同多配合物具有较优秀的抗肿瘤活性.

关键词: MTT法, 钼系杂多配合物, 抗肿瘤活性

Abstract: Antitumor activity of fifty molybdenum heteropoly compounds with different structure was studied systematically by the MTT method for the first time. The influences of heteropolyanion structure, substituent atoms and ions on antitumor acitivty were discussed. It was found that the reduction products heteropoly blue display far better antitumor activity than their parent molybdenum heteropoly compounds with Keggin structure.

Key words: MTT method, molybdenum heterepoly compound, antitumor activity