中华医学超声杂志

应用化学 ›› 1986, Vol. 0 ›› Issue (6): 68-69.

• 研究简报 • 上一篇    下一篇

用NMR方法测定三羟甲基胺基甲烷的质子解离常数

石凤, 孝延文, 倪嘉缵   

  1. 中国科学院长春应用化学研究所
  • 收稿日期:1985-12-26 修回日期:1986-03-10 出版日期:1986-12-10 发布日期:1986-12-10
  • 通讯作者: 石凤

DETERMINATION OF PROTON DISSOCIATION CONSTANT OF TRIS-(HYDROXYMETHYL)-AMINOMETHANE BY NMR METHOD

Shi Feng, Xiao Yanwen, Ni Jiazuan   

  1. Changchun Institute of Applied Chemistry, Academia Sinica
  • Received:1985-12-26 Revised:1986-03-10 Published:1986-12-10 Online:1986-12-10

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426

被引次数

1

摘要： 文献[1]中已报导了三羟甲基胺基甲烷(缓血酸胺,THAM)的质子解离常数。我们用1H和13C NMR方法研究了这一试剂的质子解离过程。

Abstract: The proton dissociation process of tris-(hydroxymethyl)-aminomethane(THAM) has been studied by 1H and 13C NMR methods.The proton dissociation constant of the title compound determined was pK=8,15, which was in good agreement with the re-sults obtained by other methods in the literature.

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