改性沸石H-BEA催化4-苯基丁酸分子内付克反应合成1-萘满酮

doi:10.3724/SP.J.1095.2011.00367

摘要/Abstract

摘要：

以乙二胺四乙酸二钠（EDTA）、柠檬酸、草酸、酒石酸改性制备了H-BEA，并根据XRD和NH3-TPD对沸石H-BEA进行表征。采用上述改性沸石催化4-苯基丁酸分子内付克反应合成1-萘满酮进行催化剂反应活性评价。实验结果表明，以柠檬酸改性沸石H-BEA具有较高的催化活性。进一步对催化剂用量、反应温度、反应时间等工艺条件优化得到最佳工艺条件，在最佳工艺条件下，产物1-萘满酮产率达到94.3%。

关键词: 苯基丁酸, 萘满酮, 分子内Friedel-Crafts, 沸石H-BEA

Abstract:

Zeolite H-BEA modified by ethylene diamine tetraacetic acid(EDTA), citric acid, oxalic acid, and tartaric acid were prepared and characterized by XRD and NH3-TPD. The catalytic performance was evaluated in the synthesis of 1-tetralone by intramolecular Friedel-Crafts reaction of 4-phenylbutyric acids. Zeolites H-BEA modified by citric acid showed high catalytic activity. In addition, the reaction conditions such as catalyst amount, reaction temperature and reaction time were examined for the optimal process conditions. Under the optimal reaction conditions, the yield for 1-tetralone was 94.3%.

Key words: henylbutyric acids, tetralones, intramolecular Friedel-Crafts, zeolites H-BEA

中图分类号:

O614.1

邱俊, 王建刚, 孙杰. 改性沸石H-BEA催化4-苯基丁酸分子内付克反应合成1-萘满酮[J]. 应用化学, 2011, 28(02): 194-198.

QIU Jun*, WANG Jiangang, SUN Jie. Synthesis of 1-Tetralones by Intramolecular Friedel-Crafts Reaction of 4-Phenylbutyric Acids Using Modified Zeolite H-BEA[J]. Chinese Journal of Applied Chemistry, 2011, 28(02): 194-198.

[1]	刘晓玲, 林淑英, 盛寿日, 辛勤, 宋才生. 3-氨基-2-羟基-4-苯基丁酸的合成[J]. 应用化学, 2005, 22(2): 222-223.
[2]	刘永军, 刘英. 2-杂萘满并喹啉衍生物的合成及其抑菌活性[J]. 应用化学, 1995, 0(4): 116-117.

改性沸石H-BEA催化4-苯基丁酸分子内付克反应合成1-萘满酮

Synthesis of 1-Tetralones by Intramolecular Friedel-Crafts Reaction of 4-Phenylbutyric Acids Using Modified Zeolite H-BEA

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