关键词: DPPH，苯并呋喃酮，抗氧性能，自由基捕获能力

Abstract:

The structure effect of benzofuranone derivatives on the scavenging ability to DPPH was studied using radical colorimetry in this paper. The results showed that: the change of methyl and tert-butyl group in 5 and 7 position of mother benzene ring of benzofuranone and the presentation of strong electron-donating substitute in substituted benzene ring have little influences on the scavenging ability of benzofuranone derivatives to DPPH. Substitute of 2’-position will prevent the attack of benzofuranone toward radicals, which weak the scavenging ability of benzofuranone derivatives to DPPH. And the scavenging ability to DPPH will be weakened further, when the substitute of 2’-position is without reactive hydrogen and can form hydrogen bond with 3- reactive hydrogen. But when the substitute of 2’-position is with reactive hydrogen, the reactive hydrogen will be actived due to the formation of hydrogen bond between substitute group with 3- reactive hydrogen, and the position hindrance will be made up in a great extent.

Key words: DPPH,benzofuranones,antioxidant activity,scavenging ability