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紫外-可见吸收、荧光光谱研究CdTe/CdS量子点与盐酸药根碱的相互作用及其应用

殷鹏飞,龚会平,刘正清,王晓丹,李萍萍,何佑秋*   

  1. (西南大学化学化工学院 重庆 400715)
  • 收稿日期:2011-04-19 修回日期:2011-06-29 出版日期:2012-03-10 发布日期:2012-03-10
  • 通讯作者: 何佑秋，教授; Tel:023-68367475; Fax:023-68254000; E-mail:heyq@swu.edu.cn; 研究方向：分子光谱分析
  • 基金资助:
    发光与实时分析重庆市重点实验室（西南大学）资助项目（CSTC，2006CA8006）

Determination of Jatrorrhizine Hydrochloride by Core-shell CdTe/CdS Quantum Dots with Fluorescence Quenching Method

YIN Pengfei, GONG Huiping, LIU Zhengqing, WANG Xiaodan, LI Pingping, HE Youqiu*   

  1. (School of Chemistry and Chemical Engineering,Southwest University,Chongqing 400715)
  • Received:2011-04-19 Revised:2011-06-29 Published:2012-03-10 Online:2012-03-10
  • Contact: Youqiu

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摘要： 合成了巯基乙酸（TGA）修饰的壳核型CdTe/CdS量子点（TGA-CdTe/CdS QDs）。 利用紫外-可见光谱吸收、荧光光谱研究TGA-CdTe/CdS QDs与盐酸药根碱（JH）的相互作用机理。 在pH值为7.4的tris-HCl缓冲溶液介质中，QDs与JH相互作用后使QDs的荧光呈线性猝灭，并有良好的线性关系（r=0.999 1），线性范围0.011~10 mg/L，检出限（3σ）为3.3×10-3 mg/L，因此可以作为一种快速、简便、定量测定盐酸药根碱的新方法。

关键词: 盐酸药根碱, 核壳型CdTe/CdS量子点, 紫外-可见吸收, 荧光猝灭法

Abstract: The mercaptoacetic acid(TGA) stabilized core-shell CdTe/CdS quantum dots(TGA-CdTe/CdS QDs) were synthesized using as stabilizer. A new method for the determination of jatrorrhizine hydrochloride has been developed based on the quenching of the fluorescence of TGA-CdTe/CdS QDs at excitation wavelength of 340 nm. The paper utilized fluorescence spectrometry and ultraviolet-visible(UV-Vis) absorption spectra to study the interaction between TGA-CdTe/CdS QDs and jatrorrhizine hydrochloride（JH）. Under optimized conditions, in which at the pH value is 7.4 using tris-HCl buffer solution, the quenched fluorescence intensity of TGA-CdTe/CdS QDs was linearly proportional with a correlation coefficient r=0.9991, and the limits of detection were in the range of 0.011~10 mg/L and the detection limit for JH(3σ) was 3.3×10-3 mg/L. JH could be conveniently and quantitatively detemined using this new method.

Key words: Jatrorrhizine hydrochloride, core-shell CdTe/CdS quantum dots, UV-Vis, fluorescence quenching

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