Chinese Journal of Applied Chemistry ›› 2016, Vol. 33 ›› Issue (7): 827-833.DOI: 10.11944/j.issn.1000-0518.2016.07.150352

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Preparation and Physicochemical Properties of the Inclusion Complexes of β-Carotene with β-Cyclodextrin and Its Derivatives

ZHOU Yehonga,MA Xuewenb,LIANG Wentingb,DONG Chuanb*(),SHUANG Shaomina*()   

  1. a Institute of Environmental Science,Shanxi University,Taiyuan 030006,China
    b School of Chemistry and Chemical Engineering,Shanxi University,Taiyuan 030006,China
  • Received:2015-10-08 Accepted:2016-01-06 Published:2016-06-30 Online:2016-06-30
  • Contact: DONG Chuan,SHUANG Shaomin
  • Supported by:
    Supported by the National Natural Science Foundation of China(No.21575084)

Abstract:

The solid inclusion complexes of β-carotene with β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin were prepared in order to improve physicochemical properties of β-carotene, such as solubility and stability. The inclusion complexes of β-carotene with β-cyclodextrin and its derivatives were characterized by UV-Vis absorption spectroscopy, Fourier-transform infrared spectroscopy and 1H NMR spectroscopy. The physicochemical properties of inclusion complexes indicate that the heat stability, light stability and antioxidant activity of β-carotene are evidently improved by the formation of inclusion complexes of β-carotene with β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin, respectively. The solubility of β-carotene increases 12 times and 18 times by the formation of inclusion complexes of β-carotene with 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin, respectively.

Key words: β-carotene, cyclodextrins, inclusion complex