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应用化学
Chinese Journal of Applied Chemistry
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Design and Preparation of Alkaloid Surface-Imprinted Material and Its Molecular Recognition Characteristics
CAO Linjiao, GAO Baojiao*, HU Weimin
(Department of Chemical Engineering,North University of China,Taiyuan 030051,China)
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Abstract  The surface-initiated graft-polymerization of glycidyl methacrylate(GMA) on micron-sized silica gel particles was first conducted with a surface-initiating system of thiol group/azodiisobutyronitrile(AIBN) to obtain PGMA-grafted SiO2 particles. Sulfonate groups were bonded onto the side chains of PGMA by ring-opening reaction between the epoxy groups of PGMA and sodium 2,4-diaminobenzene sulfonate(SAS), resulting in the formation of SAS-PGMA/SiO2 particles. The interaction between SAS-PGMA/SiO2 and matrine was examined. Surface-imprinting of the matrine molecule was performed with glutaraldehyde as the crosslinking agent to yield the matrine molecule surface-imprinted material MIP-SASP/SiO2. The experiment results show that in the nearly neutral solution, there is strong host-guest interaction between the functional grafted particles SAS-PGMA/SiO2 and matrine. The surface-imprinted MIP-SASP/SiO2 particles, have specific recognition selectivity and excellent binding affinity for matrine. Relative to the cytosine control, the coefficient of recognition selectivity of the imprinted material MIP-SASP/SiO2 for matrine reaches 10.7.
Keywords poly(glycidyl methacrylate)      silica gel      molecular surface-imprinting      matrine      molecular-recognition     
:  O631  
Issue Date: 28 August 2014
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CAO Linjiao, GAO Baojiao*, HU Weimin. Design and Preparation of Alkaloid Surface-Imprinted Material and Its Molecular Recognition Characteristics[J]. Chinese Journal of Applied Chemistry,2014, 31(12): 1390-1398.
URL:  
http://yyhx.ciac.jl.cn//EN/10.3724/SP.J.1095.2014.40070     OR     http://yyhx.ciac.jl.cn//EN/Y2014/V31/I12/1390
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