Preparation of Biodegradable Polymer Films for Prevention of Tendon Adhesion

Chinese Journal of Applied Chemistry ›› 1997, Vol. 0 ›› Issue (2): 84-86.

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Preparation of Biodegradable Polymer Films for Prevention of Tendon Adhesion

Gan Zhihua¹, Jing Xiabin¹, Zhang Zhong wen², Xu Xingxiang²

1. Polymer Physics Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022;
2. Department of O rthopaedics, Norman Bethune University of Medical Sciences, Changchun

Received:1996-07-21 Revised:1996-09-04 Published:1997-04-10 Online:1997-04-10

Abstract

Abstract: ε-Caprolactone(ε-CL)/d,l lactide(DLLA)copolymer films with thickness of 40 μm were prepared by solution-casting and implanted into rabbit body to cover the ruptured achilles tendons for preventing tendon adhesion with surrounding tissues. The biodegradation of ε-CL homopolymer film and ε-CL/DLLA copolymer film in rabbit body were also studied. The ε-CL/DLLA copolymer film could decrease postoperative adhesion of the tendon, and it degraded entirely within 24 weeks.

Key words: tendon adhesion, biodegradation, polymer film

Gan Zhihua, Jing Xiabin, Zhang Zhong wen, Xu Xingxiang. Preparation of Biodegradable Polymer Films for Prevention of Tendon Adhesion[J]. Chinese Journal of Applied Chemistry, 1997, 0(2): 84-86.

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Preparation of Biodegradable Polymer Films for Prevention of Tendon Adhesion

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