Chinese Journal of Applied Chemistry ›› 1994, Vol. 0 ›› Issue (5): 79-82.

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Synthesis of 2-Afoylamino-5-(1-phenyl-2-hydroxyanisethyl)-1,3,4-thiadiazoles

Feng Xiaoming1, Jiang Yaozhong1, Chen Rong2, Ming Liguo2   

  1. 1. Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610015;
    2. Department of CChemistry, Southwest Normal University, Chongqing
  • Received:1994-01-31 Revised:1994-03-23 Published:1994-10-10 Online:1994-10-10

Abstract: Thirteen title compounds (2) were obtained by nucleophilic addition of benzyl carbanion of 2-aroylamino-5-benzyl-1,3,4-thiadiazoles(1) with anisaldehyde in EtONa/EtOH solution. The structures of the compounds 2 were confirmed by elemental analysis, IR,1H NMR,and MS. The compounds were found to have some fungicidal activity.

Key words: thiadiazole, nucleophilic addition, fungicidal activity