Abstract: Polymer-bound α-carbanion of β-ketosulfone (2) was prepared by exchange reaction of strongly basic anion resin D296 (OH^- form) with α-pheny sulfonyl acetophenone (1).Several alkylated products of 2 were synthesized under anhydrous condition by polymer-supported carbanion with alkyl halides in good yields. The hydrolysis of the ester groupin the alkylating agent could be avoided in this process.

Key words: Polymer-bound carbanion agent, Alkylation of β-ketosulfone, Anion exchange resin