Chinese Journal of Applied Chemistry ›› 1989, Vol. 0 ›› Issue (2): 82-83.

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APPLICATION OF FLUORIDE ANION IN ORGANIC SYNTHESIS Ⅱ.PERKIN REACTION OF ACETIC ANHYDRIDE WITH BENZALDEHYDE CATALYZED BY POTASSIUM FLUORIDE

Wang Wen, Meng Fanjun, Gao Hongbin   

  1. Department of Chemistry, Shandong University, Jinan
  • Received:1988-02-04 Revised:1988-04-26 Published:1989-04-10 Online:1989-04-10

Abstract: Cinnamic acid in high yield (82.4%) was synthesized by Perkin reaction of acetic an-hydride and benzaldehyde catalyzed by anhydrous potassium fluoride. Optimum conditionsare benzaldehyde: acetic anhydride: KF = 1:3:1.5(mol ratio), reaction temperature 160±1℃ and reaction time 100 min.

Key words: Fluoride anion, Organic synthesis, Cinnamic acid, Perkin reaction