Chinese Journal of Applied Chemistry

Chinese Journal of Applied Chemistry ›› 1987, Vol. 0 ›› Issue (5): 69-71.

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SYNTHESIS AND BACTERIOSTASIS OF FURANCILIN COMPLEXES WITH COPPER(Ⅱ),ZINC(Ⅱ),AND NICKEL(Ⅱ)

Fang Yu1, Sun Zuomin1, Ren Zhu1, Xiang Jialan1, Xue Zhiwen2, Li Tong2   

  1. 1. Department of Chemistry, Shanxi Normal University;
    2. Department of Biology, Shanxi Normal University
  • Received:1986-12-29 Revised:1987-03-17 Published:1987-10-10 Online:1987-10-10

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Abstract: Five complexes [Cu(FDSC)2]Cl2, [Cu(FDTSC)2]Cl2, [Cu(N-FDSC)]Cl2], [Zn(N-FDTSC)2] and [Ni(N-FDTSC)2] have been synthesized and characterized FDSCH=N-(2-furfural)-semicarbazone,FDTSCH=N-(2- furfural)-thiosemicarbazone,N-FDSCH=N-(5-nitro-2 -furfural)-semicarbazone and N-FDTSCH=N-(5-nitro-2-furfural)-thiosemicar-bazone.It is found that N-FDSCH, N-FDTSCH, [Cu(N-FDSC)]Cl2] and [Zn(N-FDTSC)2] showed a significant bacteriostasis on Staphylococcus aureus, Bacillus subtilis and Escherichia Coli.The relationship between the bacteriostatic activity and the structure of the compounds is discussed in the paper.

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