Chinese Journal of Applied Chemistry ›› 1986, Vol. 0 ›› Issue (3): 25-29.
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Qu Yun1, Tang Wenxia1, Hu Hongwen1, Dai Anbang1, Ji Xiujuan2, Zhang Furong2, Liu Yu2
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Abstract: Seven complexes [Pt(1,3-DACH)X2] (1,3-DACH=1,3-diaminocyclohexane, X=Cl-,Br-,(1/2)Ox2-, (1/2)mal2-,AC-Cl-, (1/2)SO42-,NO3-) have been synthesized and charac-terized. It is found that [Pt(1,3-DACH)(AC-CL)2] has the strongest inhibition effect on L-1210 and S-180 in mice. The relationship between the antitumour activity and structure of the complexes is discussed.
Qu Yun, Tang Wenxia, Hu Hongwen, Dai Anbang, Ji Xiujuan, Zhang Furong, Liu Yu. SYNTHESIS,CHARACTERIZATION AND ANTITUMOUR ACTIVITY OF PLATINUM COMPLEXES OF 1,3-DIAMINOCYCLOHEXANE[J]. Chinese Journal of Applied Chemistry, 1986, 0(3): 25-29.
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