Application of Gold-nanoparticle-doped Titanium Dioxide Nanoneedle Modified Electrode for Detection of Chloramphenicol

doi:10.3724/SP.J.1095.2011.00219

Chinese Journal of Applied Chemistry ›› 2011, Vol. 28 ›› Issue (02): 240-244.DOI: 10.3724/SP.J.1095.2011.00219

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Application of Gold-nanoparticle-doped Titanium Dioxide Nanoneedle Modified Electrode for Detection of Chloramphenicol

XIN Xin, WEI Nan-Nan, LU Tian-Hong, DU Jiang-Yan^*

(Jiangsu Key Laboratory of Biofunctional Materials,College of Chemistry and Environmental Science,Nanjing Normal University,Nanjing 210046)

Received:2010-04-15 Revised:2010-07-20 Published:2011-02-10 Online:2011-02-10

Abstract

Abstract:

A gold nanoparticle-doped titanium dioxide nanoneedle modified glass carbon(Au-TiO2/GC) electrode was used for the electrochemical detection of the concentration of chloramphenicol(CAP). The results indicated that the Au-TiO2/GC electrode shows good electrochemical response for CAP in 0.1 mol/L PBS at pH=7.0. A linear relationship between the peak current and the concentration of CAP lies in the range of 8.0×10-7～1.0×10-4 mol/L with a detection limit of 7.8×10-8 mol/L. This method was applied to the detection of CAP concentration of CAP in eyedrop. It was found that this method has the high detection sensitivity, good reproducibility and ante-interference.

Key words: electroanalysis, glass carbon electrode, gold gel, titanium dioxide, chloramphenicol

CLC Number:

O657.1

XIN Xin, WEI Nan-Nan, LU Tian-Hong, DU Jiang-Yan*. Application of Gold-nanoparticle-doped Titanium Dioxide Nanoneedle Modified Electrode for Detection of Chloramphenicol[J]. Chinese Journal of Applied Chemistry, 2011, 28(02): 240-244.

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Application of Gold-nanoparticle-doped Titanium Dioxide Nanoneedle Modified Electrode for Detection of Chloramphenicol

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