国之重器：同步辐射光源驱动未来科技进步

doi:10.19894/j.issn.1000-0518.250282

摘要/Abstract

摘要：

工欲善其事，必先利其器。上海光源是我国用户最多、影响最大和产出最多的大科学装置，是当代科学研究不可或缺的尖端研究设施，极大地支撑了国家科技的创新和国际影响力的提升。近年来，上海光源推动生物医药、材料科学等领域的快速发展，10余款国产创新药上市、航空航天等战略领域材料克服关键技术瓶颈，产生了巨大的社会和经济效益。

关键词: 同步辐射光源, 大科学装置, 生物医药, 材料科学

Abstract:

A workman must first sharpen his tools if he is to do his work well. The Shanghai Synchrotron Radiation Facility （SSRF） is the largest scientific facility in China with the most users， the greatest impact， and the highest output. It is an indispensable cutting-edge research facility for contemporary scientific research and has greatly supported national technological innovation and the enhancement of international influence. In recent years， the SSRF has promoted rapid development in fields such as biomedicine and materials science， leading to the market launch of more than ten domestic innovative drugs and overcoming key technical bottlenecks in strategic areas like aerospace materials， generating significant social and economic benefits.

Key words: Synchrotron radiation facility, Large-scale scientific facilities, Biomedicine, Material science

中图分类号:

O615

王丽华, 陈建辉, 谢红兰, 汪启胜, 李爱国, 樊春海, 赵振堂. 国之重器：同步辐射光源驱动未来科技进步[J]. 应用化学, 2026, 43(1): 119-124.

Li-Hua WANG, Jian-Hui CHEN, Hong-Lan XIE, Qi-Sheng WANG, Ai-Guo LI, Chun-Hai FAN, Zhen-Tang ZHAO. National Treasure： Synchrotron Light Sources Drive Future Technological Progress[J]. Chinese Journal of Applied Chemistry, 2026, 43(1): 119-124.

图/表 5

图1 同步辐射光的产生（A）；类似于雨伞边缘沿着快速转动雨伞边缘切线方向飞出的水滴（B）及通用电气GE公司的70 MeV电子同步加速器（C）［1］

Fig.1 The generation of synchrotron light （A） is similar to droplets flying off the edge of an umbrella along the tangential direction of a rapidly spinning umbrella （B）， and the 70 MeV electron synchrotron accelerat or from General Electric （GE）（C）［1］

图2 上海同步辐射光源外景图（A）和组成（B）［2］

Fig.2 Exterior view of the SSRF （A） and its composition （B）［2］

图3 上海同步辐射光源波谱和能量范围（A）及同步辐射光与物体的相互作用（B）［3］

Fig.3 The spectral and energy range of SSRF （A） and the interaction of light with matter （B）［3］

图4 利用同步辐射生物大分子线站开展基于结构的创新药研发，推动多款国产创新药上市

Fig.4 Leveraging the macromolecular beamline for innovative drug development based on structural biology has propelled the market launch of multiple domestically developed innovative drugs

图6 X射线小角散射线站用于材料的原位无损检测。碳纤维T700预氧化和碳化过程中微结构和缺陷演变研究，揭示超倍牵伸机理研究（A）［9］；京沪高铁中高强高导铜铬锆合金接触线的凝固过程及电磁调控（B）［10］；熔盐堆先进核能系统中含钨的镍基合金制造和服役过程中应力形成机制和氧化机制（C）［11］

Fig.6 The X-ray small-angle scattering beamline is used for in-situ non-destructive testing of materials. The study of microstructural and defect evolution during the pre-oxidation and carbonization processes of T700 carbon fibers， revealing the mechanism of ultra-drawing （A）［9］； The solidification process and electromagnetic control of high-strength， high-conductivity copper-chromium-zirconium alloy contact wires used in the Beijing-Shanghai high-speed railway （B）［10］； The mechanism of stress formation and oxidation in tungsten-containing nickel-based alloys during the manufacturing and service processes of advanced molten salt reactor nuclear energy systems （C）［11］

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