蛋白质组学技术前沿进展

doi:10.11944/j.issn.1000-0518.2018.09.180208

摘要/Abstract

摘要：

蛋白质组学是以生物体系整体蛋白质为研究对象的新的研究领域,已经成为后基因时代中生命科学最重要研究方向之一。近年来,蛋白质组学研究取得了令人鼓舞的进展,一系列新技术与新方法得到了快速的发展。本文总结了2013年以来蛋白质组学研究的有关新技术,并对其发展进行了展望。

关键词: 蛋白质组, 样品预处理, 定量分析, 蛋白质相互作用

Abstract:

Proteomics, as one of the foremost branches of science in the post-genome era, is mainly focused on the expression, translational modification and interaction of proteins in cells, tissues and organs. With the rapid advancement of precision medicine and life science, higher and higher requirements have been put forward for the development of analytical methods for proteomics. Herein, we summarized the new technologies for proteome research since 2013 and prospected the future of new technics and methods for protein research.

Key words: proteome, sample preparation, protein quantification, protein-protein interaction

赵群,张丽华,张玉奎. 蛋白质组学技术前沿进展[J]. 应用化学, 2018, 35(9): 977-983.

ZHAO Qun,ZHANG Lihua,ZHANG Yukui. Recent Advances in Proteomics[J]. Chinese Journal of Applied Chemistry, 2018, 35(9): 977-983.

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