氨基酸修饰聚芳醚酮超滤膜的抗污染性能

doi:10.11944/j.issn.1000-0518.2017.06.160372

摘要/Abstract

摘要：

膜分离技术广泛应用于水处理、医药、食品、化工等领域。但在膜使用过程中,膜容易被蛋白质和细菌所污染,降低了膜的分离性能和使用寿命,提高了膜技术的应用成本,极大的限制了膜的应用。本文以含羧基的酚酞聚芳醚酮(PEK-COOH)制备超滤膜,利用1-乙基-(3-二甲基氨基丙基)碳酰二亚胺/N-羟基琥珀酰亚胺(EDC/NHS)方法将碱性氨基酸赖氨酸(Lys)、精氨酸(Arg)、组氨酸(His)接枝至超滤膜表面。实验结果表明,接枝氨基酸后水通量增加,静态蛋白吸附量降低,同时接枝组氨酸的超滤膜过滤牛血清白蛋白(BSA)3个循环后水通量恢复率达80%,表现出良好的抗污染性能。

关键词: 超滤膜, 表面接枝, 抗污染

Abstract:

Separation membrane is widely used in various separation processes such as in wastewater treatment, medicine, food and dairy processing, and chemical engineering.However, membranes are easily to be fouled by proteins and microbes, which decrease the membrane performance and lifetime. As a result, separation membranes can be expensive which inhibit it's wide use. In this study, cardo poly(aryl ether ketone) containing carboxyl(PEK-COOH) was used to fabricate ultrafiltration membrane. Lysine(Lys), arginine(Arg) and histidine(His) were introduced to the PEK-COOH membrane surface via 1-ethyl-3-(3'-dimethylaminopropyl)carbodiimide(EDC)/N-hydroxysuccinimide(NHS) method. The results show that the pure water flux increases compared with PEK-COOH membrane. Also, the amino acid modified membranes are resistant to protein adsorption. Furthermore, the flux recovery ratio of His-modified membrane is 80% after three cycles during the bovine serum albumin(BSA) solution filtration process, indicating a high antifouling property.

Key words: ultrafiltration membrane, surface-grafting, antifouling

侯淑华, 郑吉富, 董雪. 氨基酸修饰聚芳醚酮超滤膜的抗污染性能[J]. 应用化学, 2017, 34(6): 644-648.

HOU Shuhua, ZHENG Jifu, DONG Xue. Antifouling Properties of Poly(aryl ether ketone) Ultrafiltration Membranes by Surface-Grafting Amino Acids[J]. Chinese Journal of Applied Chemistry, 2017, 34(6): 644-648.

参考文献

[1]	Brans G,Schroën C G,Vander Sman R,et al. Membrane Fractionation of Milk:State of the Art and Challenges[J]. J Membr Sci,2004,243(1/2):263-272.
[2]	Cassano A,Conidi C,Drioli E. Comparison of the Performance of UF Membranes in Olive Mill WastewatersTreatment[J]. Water Res,2011,45(10):3197-3204.
[3]	Li X,Luan S,Yuan S,et al. Surface Functionalization of Styrenic Block Copolymer Elastomeric Biomaterials with Hyaluronic Acid via a “Grafting to” Strategy[J]. Colloid Surf B:Biointerfaces,2013,112:146-154.
[4]	Zhang Q,Zhang S,Dai L,et al. Novel Zwitterionic Poly(arylene ether sulfone)s as Antifouling Membrane Material[J]. J Membr Sci,2010,349(1/2):217-224.
[5]	Yu H,Kang Y,Liu Y,et al. Grafting Polyzwitterions onto Polyamide by Click Chemistry and Nucleophilic Substitution on Nitrogen:A Novel Approach to Enhance Membrane Fouling Resistance[J]. J Membr Sci,2014,449(1):50-57.
[6]	Yue W,Li H,Xiang T,et al. Grafting of Zwitterion from Polysulfone Membrane via Surface-Initiated ATRP with Enhanced Antifouling Property and Biocompatibility[J]. J Membr Sci,2013,446(11):79-91.
[7]	Zhu J,Su Y,Zhao X,et al. Improved Atifouling Properties of Poly(vinyl chloride) Ultrafiltration Membranes via Surface Zwitterionicalization[J]. Ind Eng Chem Res,2014,53(36):14046-14055.
[8]	Yuan S,Zhao J,Luan S,et al. Nuclease-Functionalized Poly(Styrene-b-isobutylene-b-styrene) Surface with Anti-Infection and Tissue Integration Bifunctions[J]. ACS Appl Mater Interfaces,2014,6(20):18078-18086.
[9]	Meng H,Cheng Q,Li C. Polyacrylonitrile-Based Zwitterionic Ultrafiltration Membrane with Improved Anti-Protein-Fouling Capacity[J]. Appl Surf Sci,2014,303(5):399-405.
[10]	Alves P,Ferreira P,Kaiser J,et al. Surface Grafting of Carboxylic Groups onto Thermoplastic Polyurethanes to Reduce Cell Adhesion[J]. Appl Surf Sci,2013,283(20):744-750.
[11]	Cai T,Li X,Wan C,et al. Zwitterionic Polymers Grafted Poly(ether sulfone) Hollow Fiber Membranes and Their Antifouling Behaviors for Osmotic Power Generation[J]. J Membr Sci,2016,497:142-152.
[12]	Wang Z,Chen T,Xu J. Novel Polyaryletherketones Containing Various Pendant Groups.Ⅰ.Synthesis and Characterization[J]. J Appl Polym Sci,1997,63(9):1127-1135.
[13]	Wang Z,Chen T,Xu J. Novel Poly(aryl ether ketone)s Containing Various Pendant Groups.Ⅱ.Gas-Transport Properties[J]. J Appl Polym Sci,1997,64(9):1725-1732.
[14]	Liu Y,Su Y,Zhao X,et al. Improved Antifouling Properties of Polyethersulfone Membrane by Blending the Amphiphilic Surface Modifier with Crosslinked Hydrophobic Segments[J]. J Membr Sci,2015,486:195-206.