中华医学超声杂志

应用化学 ›› 1991, Vol. 0 ›› Issue (3): 33-36.

• 研究论文 • 上一篇    下一篇

麦迪霉素的油/水界面循环伏安法研究及其测定

俞泽穆1, 赵宇光1, 郭渡1, 汪尔康1, 姜英夫2   

  1. 1. 中国科学院长春应用化学研究所电分析化学开放实验室, 长春 130022;
    2. 吉林省药品检验所
  • 收稿日期:1990-05-04 修回日期:1990-08-25 出版日期:1991-06-10 发布日期:1991-06-10
  • 基金资助:
    国家自然科学基金

CYCLIC VOLTAMMETRY AND DETERMINATION OF MEDEMYCIN AT WATER/OIL INTERFACES

Yu Zemu1, Zhao Yuguang1, Guo Du1, Wang Erkang1, Jiang Yingfu2   

  1. 1. Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Academia Sinica, Changchun 130022;
    2. Jilin Institute of Pharmaceutical Inspection, Changchun
  • Received:1990-05-04 Revised:1990-08-25 Published:1991-06-10 Online:1991-06-10

PDF

577

被引次数

1

摘要： 本文用循环伏安法研究了麦迪霉素推动质子从水相向硝基苯相或1,2-二氯乙烷相转移的过程,测定了麦迪霉素与质子在油相结合的稳定常数,建立了一种新的测定麦迪霉素的电化学方法。检测下限为10μg/mL,线性范围为20～1400μg/mL,样品检测结果与生物效价法相同。

关键词: 循环伏安法, 麦迪霉素, 油/水界面

Abstract: Proton transfer across water/nitrobenzene and water/1,2-dichloroethane interfaces facili-tated by medemycin has been studied using cyclic voltammetry and can be used as a rapid,simple method for determination of medemycin over the range of 20～1400μg/mL.The detec-tion limit of medemycin is 10μg/mL.Drug samples were analyzed and compared withbiological assays with satisfactory results.

Key words: cyclie voltammetry, medemycin, water/oil interface

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