应用化学 ›› 1990, Vol. 0 ›› Issue (2): 54-56.

• 研究简报 • 上一篇    下一篇

I2-KIO3-AcOH-H2O体系氧化3,5-环-24S-乙基-胆甾-22烯-6-酮反应的研究

刘兴平   

  1. 兰州大学有机化学研究所 兰州 730000
  • 收稿日期:1989-04-11 修回日期:1989-08-01 出版日期:1990-04-10 发布日期:1990-04-10

ON THE OXIDATION OF 3,5-CYCLO-24S-ETHYL-CHOLEST-22-EN-6-ONE BY I2-KIO3-AcOH-H2 O SYSTEM

Liu Xingping   

  1. Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000
  • Received:1989-04-11 Revised:1989-08-01 Published:1990-04-10 Online:1990-04-10

摘要: 油莱甾醇内酯(Brassinolide)(1)是一种高效的植物生长激素,其生理活性与侧链中C22、C23的构型密切相关。当C22、C23为S、S构型时,其活性仅为1的十分之一[1]

关键词: 碘酸钾, 氧化反应, 油菜甾醇内酯

Abstract: The oxidation of 2 by I2-KIO3-AcOH-H2O system has been studied. Instead of 3, thecisglycol(C22S, C23S)was obtained in yield of 78.5%, as the major product obtained in theoxidation of 2 by osmium tetroxide. The possible mechanism,of the oxidation reaction wasdiscussed.

Key words: potassium iodate, oxidation, brassinolide