中华医学超声杂志

应用化学 ›› 1988, Vol. 0 ›› Issue (3): 95-97.

• 研究简报 • 上一篇    

克喘素离子选择电极的研制和应用

朱世民1, 吴红1, 彭慈贞1, 胡秀贞2   

  1. 1. 南京大学化学系;
    2. 南京师范大学化学系
  • 收稿日期:1987-08-18 修回日期:1987-12-08 出版日期:1988-06-10 发布日期:1988-06-10
  • 基金资助:
    国家科学基金

CLENBUTEROLI ION SELECTIVE ELECTRODE AND ITS APPLICATION

Zhu Shimin1, Wu Hong1, Peng Cizhen1, Hu Xiuzhen2   

  1. 1. Department of Chemistry、Nanjing University;
    2. Department of Chemistry, Nanjing Normal University
  • Received:1987-08-18 Revised:1987-12-08 Published:1988-06-10 Online:1988-06-10

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摘要： 克喘素(Clenbuteroli)化学名盐酸双氯醇胺,是一种治疗支气管哮喘等病症的新药.程大敦等曾用萃取紫外分光光度法测定它的含量.本文研制了四苯硼-克喘素和二苦胺-克喘素离子选择电极,两种电极对克喘素均有良好的响应特性,可用于克喘素原药及其片剂含量的快速分析.

关键词: 克喘素, 四苯硼-克喘素离子缔合物, 二苦胺-克喘素离子缔合物, PVC膜电极

Abstract: The PVC membrane ion selective electrodes for clenbuteroli using tetraphenylborateclenbuteroli(Ⅰ) and dipicrYlamine-clenbuteroli(Ⅱ) ion pair complex as the active materials were studied.The nernst responses are 1×10-5-1×102 and 4×10-5- 1×10-2mol/l respectively for electrode (Ⅰ) and(Ⅱ) with slope of 55-57 mV/pC, both they showed rapid response, good reproducibility and stabitity. The selectivity coefficients of 16 substances were determined.

Key words: Clenbuteroli, Ion Pair eomplexes, PvC membrane electrode

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