葡萄糖敏感苯硼酸基高分子纳米药物传输体系

黄琼卫^a, 赵丽^b, 宋之明^c, 冯祥汝^d, 王清^a, 丁建勋^d,^*

Phenylboronic Acid-Based Glucose-Sensitive Polymer Nanocarriers Used as Drug Delivery Systems

HUANG Qiongwei^a, ZHAO Li^b, SONG Zhiming^c, FENG Xiangru^d, DING Jianxun^d

P(AA- co-APBA)/P(AA- co-AGA)复合微凝胶粒的形成和葡萄糖响应性崩解示意图( A)。在pH=7.4,葡萄糖浓度=2 g/L的PBS中,不同比例PEG- b-P(AA- co-APBA)/P(AA- co-AGA)( w/w)复合胶束的葡萄糖响应性( B)^[41]