Chinese Journal of Applied Chemistry ›› 2021, Vol. 38 ›› Issue (4): 367-375.DOI: 10.19894/j.issn.1000-0518.200321

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Research Progress on the Interaction Between Natural Products and Intestinal Microbes

LIU Ming, SONG Feng-Yuan, LI Fang-Tong, YANG Di, YUE Hao, DAI Yu-Lin, ZHENG Fei*, HUANG Xin*   

  1. Changchun University of Chinese Medicine, Jilin Ginseng Academy, Changchun 130117, China
  • Online:2021-06-01
  • Supported by:
    Supported by the National Key Research and Development Project (No.2017YFC1702105), Jilin Provincial Science and Technology Department of China (No.20200201141JC) and Young Scientists Development Program of “Xinglin Scholar Project” of Changchun University of Chinese Medicine

Abstract: The intestinal flora plays a vital role in the health of the human body, and imbalance will induce a variety of diseases. Natural products have been proven to prevent and treat a variety of diseases by regulating the balance of intestinal flora, but the specific mechanism of action is still unclear. This article mainly reviews the interactions of saponins, flavonoids, alkaloids and polysaccharides in natural products with intestinal flora, and summarizes their metabolites and metabolic pathways, with a view to further research on natural products to regulate the intestinal tract. The mechanism of action of the flora provides a reference.

Key words: Intestinal flora, Natural product, Metabolism, Mechanism

CLC Number: